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Houses for Rent in South Main, Houston, TX

Average rent

$2,225

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11504 Main Pine Dr - Photo 1 of 1

5d+ ago

South Main house for rent in Houston

11504 Main Pine Dr, Houston, TX 77025

In-unit laundry | Walk-in closets | Dishwasher

3 beds

2 baths

$2,400

House for rent

11608 Main Ash - Photo 1 of 1

5d+ ago

South Main townhouse for rent in Houston

11608 Main Ash, Houston, TX 77025

On-site laundry | Garage parking | High ceilings

3 beds

2 baths

$2,195

House for rent

Available Jul 21

11603 Main Spruce Drive #NA - Photo 1 of 1

5d+ ago

South Main house for rent in Houston

$2,100 - 3 Bedroom 2.5 Bathroom House Close to Texas Medical Center

11603 Main Spruce Drive #NA, Houston, TX 77025

In-unit laundry | Garage parking | Air conditioning

3 beds

2 baths

$2,100

House for rent

Available Jan 5

11510 Main Ash #11510 - Photo 1 of 1

5d+ ago

South Main townhouse for rent in Houston

3 BR, 3 BA in South Main

11510 Main Ash #11510, Houston, TX 77025

On-site laundry | High ceilings | Hardwood floor

3 beds

3 baths

$2,300

House for rent

Available Nov 11

2615 Cheshire Oaks Dr - Photo 1 of 1

5d+ ago

South Main house for rent in Houston

2615 Cheshire Oaks Dr, Houston, TX 77054

Outdoor space | Swimming pool | Fitness center

4 beds

3 baths

$2,700

House for rent

9295 Buffalo Speedway - Photo 1 of 1

5d+ ago

Braeswood Place house for rent in Houston

9295 Buffalo Speedway, Houston, TX 77025

In-unit laundry | Garage parking | Air conditioning

3 beds

2 baths

$3,000

House for rent

Description

Located in a quiet, gated community, this beautifully maintained 3-bedroom, 2.5-bath home offers approximately 2,500 square feet of living space. Enjoy unbeatable proximity to the Texas Medical Center, NRG Stadium, and easy access to the 610 Loop, making commuting and city living effortless. Surrounded by abundant dining, shopping, and entertainment options, this home delivers both convenience and comfort in one of Houston’s most desirable locations. A brand-new washer, dryer, and refrigerator are in the process of being purchased and will be installed and fully connected

Nearby rental good for eco-living

Nearby rental good for pet owners

Listings within 5 miles
9606 Ashville Dr #B - Photo 1 of 1

5d+ ago

Sunnyside house for rent in Houston

9606 Ashville Dr #B, Houston, TX 77051

On-site laundry | Outdoor space | Garage parking

3 beds

2 baths

$1,725

House for rent

Description

Modern Duplex minutes from Downtown - 3/2 home with large backyard and private garage. Located just 10 minutes from Reliant Stadium, with direct access to the Texas Medical Center and Downtown Houston!. Includes Refrigerator, range, dishwasher, and more!. Note: Vouchers are accepted All residents are enrolled in the Resident Benefits Package for $35 a month, which includes HVAC filter delivery, general liability protection, utility concierge services, renters insurance, and more! See Agent or Screening Criteria for details. *Agent Commission Information* Agents must be p

7902 Parnell St - Photo 1 of 1

5d+ ago

Sunnyside house for rent in Houston

House for rent

Description

✨ Move-In Special: $500 off your first month’s rent! ✨ Welcome home to this beautiful 3-bedroom, 2.5-bath Houston property that blends comfort, space, and everyday convenience. Designed with an inviting open-concept layout, this home offers a bright and spacious living area perfect for relaxing, entertaining, or enjoying time with family and friends. The functional kitchen provides ample room for meal prep and daily living, with a layout that keeps you connected to the main living space. You’ll also enjoy the convenience of washer and dryer connections, making laundry d

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4031 Leeshire Dr - Photo 1 of 1
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1d ago

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4031 Leeshire Dr, Houston, TX 77025

On-site laundry | Outdoor space | Hardwood floor

Studio

1 bath

$1,211

$1,090

Price drop

House for rent

Available Dec 1

Description

This property is available. Please inquire on this site to schedule a showing. Welcome to your new home at 4031 Leeshire Drive in Houston, TX! This charming property features a striking red door that opens into a spacious, light-filled living area with modern wood flooring and a ceiling fan for added comfort. The open-concept kitchen is a chef's delight, boasting sleek granite countertops, stainless steel appliances, and crisp white cabinetry, all underlined by a stylish tile backsplash. The seamless integration of the kitchen and living space makes it perfect for both ev

3410 Brookston St - Photo 1 of 1

5d+ ago

Our team has verified this company

Verified

3410 Brookston St, Houston, TX 77045

Outdoor space | Storage | Garage parking

3 beds

2 baths

$1,550

House for rent

Description

Fall in LOVE with an exclusive offer! Apply by February 12th and take advantage of our special offer. Ask for details today! Restrictions apply. Welcome to this 3-bedroom, 2-bathroom home for rent in Houston featuring inviting living areas ready for your personal touch. The kitchen is equipped with an oven range and large refrigerator with storage for daily meal prep, plus the spacious living area provides room for comfortable relaxation. Flooring varies, with a mix of hard surfaces or carpeting throughout the home and high-quality air filtration through Second Nature. Th

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These rentals are 10%-30% cheaper than the local average price for similar rentals.

10510 Cathedral Drive #1 - Photo 1 of 1

5d+ ago

Sunnyside house for rent in Houston

10510 Cathedral Drive - 1

10510 Cathedral Drive #1, Houston, TX 77051

3 beds

1 bath

$1,300

House for rent

Available Jan 1

Description

This 887 square foot single family home has 3 bedrooms and 1.0 bathrooms. This home is located at 10510 Cathedral Dr, Houston, TX 77051.

9315 Ashville Dr #B - Photo 1 of 1

5d+ ago

Sunnyside townhouse for rent in Houston

9315 Ashville Dr #B, Houston, TX 77051

In-unit laundry | Dishwasher

3 beds

3 baths

$1,800

House for rent

Description

MOVE IN SPECIAL 50% off 3rd Month. Discover modern townhome living just minutes from the Texas Medical Center in this newly built residence now available for lease. Thoughtfully designed for comfort and style, this home features an open-concept kitchen and living area. The kitchen is equipped with sleek Energy Star stainless steel appliances, granite countertops, and contemporary cabinetry. Upstairs, the primary bedroom serves as a private retreat with an ensuite bathroom featuring a stand-up shower and dual sinks. Two additional bedrooms offer ample space and share a well

4413 Santorini Ln #NA - Photo 1 of 1

1d ago

Central Southwest house for rent in Houston

4413 Santorini Ln #NA, Houston, TX 77045

In-unit laundry | Outdoor space | Garage parking

3 beds

2 baths

$2,500

House for rent

Available Jan 18

Description

Spacious 3-bedroom, 2.5-bath multi-level home offering approximately 1,700 sq ft of living space, featuring quartz kitchen countertops, tile flooring on the main level, and laminate flooring throughout the second floor. The home includes walk-in closets, full showers, central heating and air conditioning, and a 2-car attached garage. Enjoy a private fenced yard, deck, and access to nearby dog park and walking trails. Appliances include washer, dryer, microwave, dishwasher, refrigerator, garbage disposal, along with ceiling fans and cable-ready connections. Pets are accepte

7575 Cambridge St #1 - Photo 1 of 1

5d+ ago

Astrodome townhouse for rent in Houston

7575 Cambridge Street #1902 - 1

7575 Cambridge St #1, Houston, TX 77054

2 beds

1 bath

$1,500

House for rent

Available Jan 13

Description

Fantastic Med Center location at an affordable price point — right across the street from UT Health Houston School of Dentistry! Property rent "AS IS". This spacious 2-bedroom unit offers a great floor plan, ideal for a student, investor, young professional, or small family. Nestled in a quiet corner of the community. Washer, dryer, and refrigerator will remain with the property in their current condition. Tenant turns on utilities antastic Med Center location at an affordable price point — right across the street from UT Health Houston School of Dentistry! Property rent "

4718 N Braeswood Blvd - Photo 1 of 1

5d+ ago

Meyerland Area house for rent in Houston

4718 N Braeswood Blvd, Houston, TX 77096

In-unit laundry | Outdoor space | Swimming pool

4 beds

4 baths

$4,700

House for rent

Description

This beautifully updated home at 4718 N Braeswood Blvd offers 4 bedrooms, 4.5 bathrooms, and 2,383 square feet of living space in a prime Houston location. The interior has been tastefully updated and is truly move-in ready, with a layout that works well for both everyday living and entertaining. Out back, you’ll find a spacious yard with a pool, giving the home a private, relaxing feel that’s perfect for hosting friends or unwinding after a long day. Even though it’s centrally located, the property feels tucked away and peaceful. The location is hard to beat, just a con

10747 Dulcimer St - Photo 1 of 1

5d+ ago

Sunnyside house for rent in Houston

Furnished 5 bed with Garage Apartment

10747 Dulcimer St, Houston, TX 77051

In-unit laundry | Outdoor space | Assigned parking

5 beds

3 baths

$5,200

House for rent

Available Jan 6

Description

Property Id: 2308573 Rent our beuatiful fully furnished home on a weekly or monthly basis. - Pets allowed on a case-by-case basis for a fee. - Renting over 30 days requires a back-ground check. - Optional to rent via various booking platforms as well as via owner. - Rent includes internet, electricity, water, trash, and basic disposalables like shampoo, soap, towels, pillows, linens, etc. Our country style home with 5 bedrooms is located just south of Downtown Houston off HWY 288. Our home is less than half a mile (2 minutes) to 288 HWY, ensuring easy and quick access t

8230 Woodward St - Photo 1 of 1

5d+ ago

Sunnyside house for rent in Houston

House for rent

Description

Beautiful Home In Houston. Move In Ready!. Beautifully renovated 4 bedroom, 2 bathroom home located in Houston, Tx. This home figures beautiful tile floors, granite counter tops. This property will not last. Please call Today 409-420-1022 and/or email: **** Apply at: https ezrental4you appfolio com listings Application Fee $55 Aged 18 And Older, No Evictions Or Oustanding Rent Payment History In The Past 5 Years, No Criminal Convictions In The Past 10 Years, Including Misdememeanors Of Any Kind. Income Requirements Combined Income Must Be At Least 3 Times The Monthly Re

3034 Akard St #1 - Photo 1 of 1

5d+ ago

Sunnyside house for rent in Houston

3034 Akard Street - 1

3034 Akard St #1, Houston, TX 77051

In-unit laundry | Air conditioning | Central heat

4 beds

2 baths

$1,795

House for rent

Available Jan 3

Description

Step into this beautifully updated and spacious 4-bedroom, 2-bath home offering an impressive 1,755 square feet of well-designed living. Located just minutes from the Texas Medical Center, NRG, and major freeways, this home delivers both comfort and convenience. Inside, you'll find a bright, inviting layout featuring a generous family room overlooking the backyard, a dedicated formal living room, and a separate dining room. The kitchen opens to the family room and includes ample counter space, updated cabinetry, and great natural light. The primary bedroom features easy ac

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3325 Tampa St - Photo 1 of 1

5d+ ago

MacGregor house for rent in Houston

3325 Tampa St, Houston, TX 77021

In-unit laundry | Dishwasher | Microwave

1 bed

1 bath

$650

House for rent

Available Jan 1

Description

Property Id: 1433047 Large spacious room in sough after area near medical center, downtown, University of Houston and University of St Thomas campuses. ALL Bills Paid. In unit Washer Dryer , central air and heating. Large spacious kitchen

7447 Cambridge St - Photo 1 of 1

5d+ ago

Astrodome townhouse for rent in Houston

2 BR, 3 BA in Astrodome

7447 Cambridge St, Houston, TX 77054

Fireplace | Furnished

2 beds

3 baths

$3,350

House for rent

Available Dec 9

Description

Set just beyond the energy of the Med Center, this completely remodeled townhome offers a sense of seclusion within a gated community while keeping every Houston convenience within reach. Inside, a full sweep of updates elevates the interior—new flooring, crisp paint, and refined surfaces creating a clean, modern backdrop. Sunlight filters through the generous layout, highlighting airy rooms, purposeful storage, and a central atrium that doubles as a quiet hideaway for coffee, reading, or open-sky relaxation. Both the main living area and the upstairs suite feature firepla

9663 Kings Cross Sta #9663 - Photo 1 of 1

5d+ ago

Central Southwest townhouse for rent in Houston

$3,200 - 3 Bedroom 3.5 Bathroom Townhouse near Medical Center

9663 Kings Cross Sta #9663, Houston, TX 77045

In-unit laundry | Garage parking | Air conditioning

3 beds

3 baths

$3,201

House for rent

Available Jan 1

Description

Sophistication greets you from the moment you step inside this elegant 3-bedroom home with 3.5 baths and a dedicated office, offering an inviting setting for both everyday comfort and gracious hosting. An airy living area sits at the heart of the layout, featuring a warm fireplace and generous space for gathering, conversation, and quiet evenings in. The patio is perfect for relaxing to watch the sunset. Each of the three bedrooms is thoughtfully designed for privacy and comfort, complemented by 3.5 beautifully appointed bathrooms. The dedicated office provides a tranquil

8299 Cambridge St - Photo 1 of 1

5d+ ago

Astrodome townhouse for rent in Houston

2 BR, 2 BA in Sherbrooke Square Townhome Condominiums

8299 Cambridge St, Houston, TX 77054

In-unit laundry | Assigned parking | Carpet

2 beds

2 baths

$1,300

House for rent

Available Nov 26

Description

This gorgeous 2-bed townhome is in the heart of the Texas Medical Center and a prime example of urban living at its best. The first floor has an updated kitchen featuring stainless steel appliances, a pantry, and granite countertops that opens to the spacious living area with a cozy fireplace. The second floor has the primary suite with plush carpeting and an exceptional ensuite with built-ins and a soaking tub with a shower combo. A secondary bedroom could be used as an office or flex space. With all washer, dryer, and fridge included, it's move-in ready. Sherbrooke Squar

10117 Dulcimer St - Photo 1 of 1

5d+ ago

Sunnyside house for rent in Houston

3 beds

1 bath

$1,450

House for rent

Description

Nice 3 bedroom home that is conveniently situated near local stores and easy access to us 288. The family area is a good size with plenty of light. The kitchen has a breakfast area. The garage has been converted to a third bedroom. Large yard/lot for the area.

6742 Peerless St #B - Photo 1 of 1
New construction

5d+ ago

OST - South Union house for rent in Houston

Detached,Traditional, Detached - Houston, TX

6742 Peerless St #B, Houston, TX 77021

In-unit laundry | Garage parking | High ceilings

3 beds

3 baths

$2,350

$2,250

Price drop

House for rent

Description

Property Status: Active Welcome to Peerless Court! This residence offers 3 bedrooms and 3.5 baths, thoughtfully designed with modern finishes throughout. Interior features include engineered hardwood flooring, quartz countertops, stainless steel appliances, and modern shaker cabinets and hardware. The home combines comfort and style in a prime Houston location, offering easy access to dining, shopping, minutes from the Medical Center and Downtown. Office Phone: (281) 652-5588 Copyright © 2026 Houston Realtors Information Service. All rights reserved. All information provid

2807 Glengary River Way - Photo 1 of 1

5d+ ago

Sunnyside house for rent in Houston

2807 Glengary River Way, Houston, TX 77051

In-unit laundry | Controlled access | Dishwasher

3 beds

2 baths

$2,350

House for rent

Description

This recently completed 3 bedroom, 2.5 bathroom home is located in a gated community close to 288 between downtown and Pearland. Be the first to call this house your home as you enjoy the convenience of being within close driving distance to 288, 610, the medical center and Hobby Airport. This house sits on a corner lot and includes, washer, dryer, and refrigerator. See this property and make it your home!

Showing 1 - 25 of 25 results
Home > House Rentals in Houston > South Main Houses For Rent
Updated: January 20, 2026

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Discover houses for rent in South Main, Houston, TX

🌇Available house rentals25 houses
💰Best rent deal11603 Main Spruce Drive #NA
🍃With outdoor space
Popular amenities, ,
🍽With dishwasher
🚗With garage parking
❄️With air conditioning
🏠With photos