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Luxury Houses for Rent in Seneca, SC

25 rentals

512 Andrew Pickens Dr - Photo 1 of 1

5d+ ago

Luxury house for rent in Seneca

3 bedroom house for rent

512 Andrew Pickens Dr, Seneca, SC 29678

Luxury | In-unit laundry | Outdoor space

3 beds

2 baths

$2,000

House for rent

Available Mar 1

Top amenities
Hardwood Floor
In-Unit Laundry
309B Dixie Dr - Photo 1 of 1

5d+ ago

Luxury house for rent in Seneca

SINGLE_FAMILY - Seneca, SC

309B Dixie Dr, Seneca, SC 29672

Luxury

1 bed

1 bath

$1,100

House for rent

364 Fiddlers Way - Photo 1 of 1

5d+ ago

Luxury house for rent in Seneca

364 Fiddlers Way, Seneca, SC 29678

Luxury | In-unit laundry | Dishwasher

4 beds

2 baths

$3,100

House for rent

Top amenities
In-Unit Laundry
1251 S Oak St - Photo 1 of 1

5d+ ago

Luxury house for rent in Seneca

SINGLE_FAMILY - Ranch - Seneca, SC

1251 S Oak St, Seneca, SC 29678

Luxury | Carpet

3 beds

2 baths

$1,950

House for rent

109A Towe St - Photo 1 of 1

5d+ ago

Luxury house for rent in Seneca

MANUFACTURED - Other - Seneca, SC

109A Towe St, Seneca, SC 29678

Luxury | Outdoor space | Dishwasher

2 beds

2 baths

$1,300

House for rent

247 Wimbledon Way - Photo 1 of 1

5d+ ago

Luxury house for rent in Seneca

SINGLE_FAMILY - Other - Seneca, SC

247 Wimbledon Way, Seneca, SC 29678

Luxury | Garage parking | Carpet

3 beds

2 baths

$1,900

House for rent

Nearby rental good for eco-living

Nearby rental good for pet owners

$1,000

Clemson

249 Carvel Trl - Photo 1 of 1

5d+ ago

Luxury house for rent in Seneca

SINGLE_FAMILY - Other - Seneca, SC

249 Carvel Trl, Seneca, SC 29678

Luxury | In-unit laundry | Garage parking

4 beds

2 baths

$2,800

House for rent

Top amenities
Dishwasher
In-Unit Laundry
109 Oakmont Valley Trl - Photo 1 of 1

5d+ ago

Luxury townhouse for rent in Seneca

109 Oakmont Valley Trl, Seneca, SC 29678

Luxury | Storage | Furnished

1 bed

1 bath

$875

House for rent

Available Nov 1

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123 Perkins Pl - Photo 1 of 1

18h ago

Luxury townhouse for rent in Seneca

TOWNHOME - Seneca, SC

123 Perkins Pl, Seneca, SC 29678

Luxury | On-site laundry | Outdoor space

3 beds

2 baths

$1,495

House for rent

Top amenities
On-Site Laundry
550 J P Stevens Rd - Photo 1 of 1

5d+ ago

Luxury house for rent in Seneca

SINGLE_FAMILY - Contemporary - Seneca, SC

550 J P Stevens Rd, Seneca, SC 29678

Luxury | In-unit laundry | Ceiling fan

4 beds

3 baths

$1,900

House for rent

Top amenities
In-Unit Laundry
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759 Bellview Way - Photo 1 of 1

5d+ ago

Luxury townhouse for rent in Seneca

3 Bed Townhouse in Seneca | 2.5 Bath | $1500 | Available 02/15 - 759 Bellview Way

759 Bellview Way, Seneca, SC 29678

Luxury | In-unit laundry | Carpet

3 beds

2 baths

$1,500

House for rent

Available Feb 15

Top amenities
Carpet
In-Unit Laundry
738 Old Clemson Hwy Lot 28 - Photo 1 of 1

5d+ ago

Luxury house for rent in Seneca

Hartwell Lake Park - w28 - 738/28OCH

738 Old Clemson Hwy Lot 28, Seneca, SC 29672

Luxury | Walk-in closets | On-site laundry

3 beds

2 baths

$1,200

House for rent

Available Dec 18

Top amenities
Ceiling Fan
On-Site Laundry
443 Old Clemson Highway - Photo 1 of 1

5d+ ago

Luxury house for rent in Seneca

443 Old Clemson Highway, Seneca, SC 29672

Luxury | In-unit laundry | Dishwasher

3 beds

2 baths

$1,400

House for rent

Top amenities
In-Unit Laundry
304 Cottage Hill Ct - Photo 1 of 1
New construction

5d+ ago

Luxury house for rent in Seneca

SINGLE_FAMILY - Cottage, Craftsman - Seneca, SC

304 Cottage Hill Ct, Seneca, SC 29678

Luxury | Walk-in closets | In-unit laundry

3 beds

2 baths

$1,750

House for rent

Top amenities
Garage Parking
High Ceilings
In-Unit Laundry
Storage
37 Sirrine St - Photo 1 of 1

5d+ ago

Luxury house for rent in Seneca

37 Sirrine St, Seneca, SC 29678

Luxury | In-unit laundry | On-site laundry

2 beds

1 bath

$875

House for rent

Available Dec 10

Top amenities
High Ceilings
In-Unit Laundry
On-Site Laundry
On-Site Management
Package Service
Storage
Listings within 10 miles
108 Clemson Street - Photo 1 of 1

5d+ ago

Luxury townhouse for rent in Clemson

108 Clemson Street, Clemson, SC 29631

Luxury | In-unit laundry | Garage parking

4 beds

5 baths

$4,000

House for rent

Top amenities
Dishwasher
In-Unit Laundry
600 Anderson Hwy #313 - Photo 1 of 1

5d+ ago

Luxury townhouse for rent in Clemson

600 Anderson Hwy #313, Clemson, SC 29631

Luxury

3 beds

3 baths

$2,025

House for rent

Available Aug 15

102 Franklin Dr - Photo 1 of 1

5d+ ago

Luxury house for rent in Central

102 Franklin Dr, Central, SC 29630

Luxury | Oven

1 bed

1 bath

$625

House for rent

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126 Heritage Place Dr - Photo 1 of 1

5d+ ago

Luxury house for rent in Pendleton

126 Heritage Place Dr, Pendleton, SC 29670

Luxury | Outdoor space

3 beds

3 baths

$1,900

House for rent

Available Jan 10

100 Lakeview Cir - Photo 1 of 1

5d+ ago

Luxury house for rent in Clemson

100 Lakeview Cir, Clemson, SC 29631

Luxury | In-unit laundry | Dishwasher

3 beds

2 baths

$2,000

House for rent

Top amenities
In-Unit Laundry
1108 Tiger Blvd - Photo 1 of 1

5d+ ago

Luxury townhouse for rent in Clemson

1108 Tiger Blvd, Clemson, SC 29631

Luxury

2 beds

1 bath

$1,150

House for rent

107 Franklin Dr - Photo 1 of 1

5d+ ago

Luxury house for rent in Central

107 Franklin Dr, Central, SC 29630

Luxury | In-unit laundry | Dishwasher

3 beds

2 baths

$1,500

House for rent

Top amenities
In-Unit Laundry
406 Rock Creek Rd - Photo 1 of 1

5d+ ago

Luxury house for rent in Clemson

406 Rock Creek Rd, Clemson, SC 29631

Luxury | In-unit laundry | Dishwasher

3 beds

2 baths

$1,800

House for rent

Top amenities
In-Unit Laundry
112 Elm St - Photo 1 of 1

5d+ ago

Luxury house for rent in Clemson

112 Elm St, Clemson, SC 29631

Luxury | In-unit laundry | Dishwasher

4 beds

2 baths

$1,900

House for rent

Top amenities
In-Unit Laundry
204 Calhoun St #22 - Photo 1 of 1

5d+ ago

Luxury house for rent in Clemson

Luxury | Walk-in closets | In-unit laundry

1 bed

1 bath

$925

House for rent

Available Aug 15

Top amenities
In-Unit Laundry
On-Site Laundry
Showing 1 - 25 of 25 results
Home > House Rentals in Seneca > Seneca Luxury Houses For Rent
Updated: January 21, 2026

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Pet friendly houses in Seneca, SC5 rentals

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Discover luxury Seneca, SC houses for rent

🌇Available luxury house rentals25 houses
⭐Popular amenities, ,
🍽With dishwasher
❄️With air conditioning
🚗With garage parking
🍃With outdoor space
🏠With photos