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Houses for Rent in Defiance, MO

Average rent

$2,300

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416 Oak Pl - Photo 1 of 1

2d ago

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Verified

416 Oak Pl, Lake St. Louis, MO 63367

On-site laundry | Swimming pool | Balcony

5 beds

3 baths

$2,970

House for rent

Available May 13

2005 Briarridge Dr - Photo 1 of 1

3d ago

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Verified

2005 Briarridge Dr, Lake St. Louis, MO 63367

On-site laundry | Swimming pool | On-site management

4 beds

2.5 baths

$2,975

House for rent

Available May 12

611 Lakewood Dr - Photo 1 of 1

5d+ ago

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Verified

611 Lakewood Dr, Lake St. Louis, MO 63367

On-site laundry | Swimming pool | On-site management

3 beds

3 baths

$2,555

House for rent

Available May 8

1 Hunters Pass Ct - Photo 1 of 1

5d+ ago

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Verified

1 Hunters Pass Ct, Saint Peters, MO 63376

On-site laundry | Swimming pool | On-site management

4 beds

2.5 baths

$3,055

House for rent

Available Apr 21

2322 Marbury Way - Photo 1 of 1

5d+ ago

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Verified

2322 Marbury Way, O'Fallon, MO 63368

On-site laundry | Swimming pool | Balcony

4 beds

3 baths

$3,190

$3,000

Price drop

House for rent

Available Mar 31

1012 Glengarry Dr - Photo 1 of 1

5d+ ago

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Verified

1012 Glengarry Dr, Wentzville, MO 63385

On-site laundry | Swimming pool | Balcony

4 beds

2 baths

$2,665

$2,530

Price drop

House for rent

Available Apr 6

Nearby rental good for eco-living

$1,750

O'Fallon

Nearby rental good for pet owners

$2,825

Oakridge Estates

616 Autumnwood Forest Dr - Photo 1 of 1

5d+ ago

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Verified

616 Autumnwood Forest Dr, Lake St. Louis, MO 63367

On-site laundry | Swimming pool | On-site management

3 beds

2 baths

$2,960

$2,795

Price drop

House for rent

Available Mar 2

6303 Spring River Dr - Photo 1 of 1

4d ago

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Verified

6303 Spring River Dr, O'Fallon, MO 63368

In-unit laundry | Outdoor space | Assigned parking

2 beds

2 baths

$1,750

House for rent

Available Jan 12

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538 Springhurst Pkwy - Photo 1 of 1

5d+ ago

House for rent in O'Fallon

Single Family Residence, Traditional - O'Fallon, MO

538 Springhurst Pkwy, O'Fallon, MO 63368

In-unit laundry | Outdoor space | Garage parking

3 beds

3.5 baths

$2,495

House for rent

301 Quail Hollow Dr - Photo 1 of 1
Rent special

5d+ ago

House for rent in O'Fallon

Limited Time Special Offer / Spacious 4-Bed Home with 2-Car Garage & Modern Amenities

301 Quail Hollow Dr, O'Fallon, MO 63368

Garage parking | Fireplace | Ceiling fan

4 beds

3 baths

$3,445

House for rent

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Find sweet deals near Defiance

These rentals are 10%-30% cheaper than the local average price for similar rentals.

$2,300

Wentzville

$2,800

Lake Saint Louis

$1,950

O'Fallon

$1,950

Lake Saint Louis

56 Helena Ct - Photo 1 of 1

5d+ ago

House for rent in Wentzville

House for rent

4 Inverness Ct - Photo 1 of 1
3D tour

5d+ ago

House for rent in Saint Peters

3 Bedroom Pet-Friendly Home in St. Peters, MO with Main Street Renewal

4 Inverness Ct, Saint Peters, MO 63376

Outdoor space | Storage | Swimming pool

3 beds

2 baths

$2,405

House for rent

331 Carriage Trail Ct - Photo 1 of 1

5d+ ago

House for rent in O'Fallon

Single Family Residence, Contemporary,Ranch - O'Fallon, MO

331 Carriage Trail Ct, O'Fallon, MO 63368

In-unit laundry | Outdoor space | Garage parking

5 beds

3 baths

$2,800

House for rent

46 Freymuth Rd #NA - Photo 1 of 1

5d+ ago

Lake Saint Louis house for rent in Lake St. Louis

$2,800 - 4 Bedroom 3 Bathroom House In Lake Saint Louis With Lake Rights

46 Freymuth Rd #NA, Lake St. Louis, MO 63367

In-unit laundry | Outdoor space | Garage parking

4 beds

3 baths

$2,800

House for rent

Available Apr 1

643 Country Heights Dr - Photo 1 of 1

5d+ ago

Lake Saint Louis townhouse for rent in Lake St. Louis

Townhouse, Traditional - Lake St Louis, MO

643 Country Heights Dr, Lake St. Louis, MO 63367

On-site laundry | Outdoor space | Storage

3 beds

2.5 baths

$2,095

House for rent

596 Misty Mountain Dr - Photo 1 of 1

5d+ ago

House for rent in O'Fallon

Single Family Residence, Traditional - O'Fallon, MO

596 Misty Mountain Dr, O'Fallon, MO 63368

In-unit laundry | Outdoor space | Garage parking

3 beds

2.5 baths

$2,300

House for rent

6 Royallcrest Ct - Photo 1 of 1

5d+ ago

House for rent in O'Fallon

Single Family Residence - O'Fallon, MO

6 Royallcrest Ct, O'Fallon, MO 63368

Outdoor space | Garage parking | Carpet

4 beds

2.5 baths

$2,500

House for rent

221 Cherrywood Parc Dr - Photo 1 of 1

5d+ ago

House for rent in O'Fallon

221 Cherrywood Parc Dr, O'Fallon, MO 63368

Outdoor space | On-site management

3 beds

3.5 baths

$2,395

House for rent

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3119 Post Run Dr - Photo 1 of 1

5d+ ago

House for rent in O'Fallon

3119 Post Run Dr, O'Fallon, MO 63368

In-unit laundry | Outdoor space | Garage parking

3 beds

3 baths

$2,650

House for rent

Available Mar 2

511 Chapparal Dr - Photo 1 of 1

5d+ ago

House for rent in O'Fallon

Charming 3 Bed/2 Bath Single Family Home in O'Fallon, MO

511 Chapparal Dr, O'Fallon, MO 63368

In-unit laundry | Outdoor space | Garage parking

3 beds

2 baths

$2,400

House for rent

Available Jan 6

2606 Walnut Ave - Photo 1 of 1

5d+ ago

Glencoe house for rent in Wildwood

Single Family Residence, Ranch - Wildwood, MO

2606 Walnut Ave, Wildwood, MO 63038

Outdoor space | Storage | Ceiling fan

2 beds

1 bath

$1,800

House for rent

156 Far Meadow Dr #NA - Photo 1 of 1

5d+ ago

House for rent in Wentzville

$3,998 - 5 Bedroom 4 Bathroom House In O'Fallon With Great Amenities

156 Far Meadow Dr #NA, Wentzville, MO 63367

In-unit laundry | Outdoor space | Garage parking

5 beds

4 baths

$3,998

House for rent

Available Dec 19

9970 Highway N #B1 - Photo 1 of 1

5d+ ago

Townhouse for rent in Wentzville

9970 Hwy. 165 N Residential - B-1

9970 Highway N #B1, Wentzville, MO 63367

In-unit laundry | Air conditioning | Central heat

2 beds

2 baths

$1,650

House for rent

Available Jan 1

221 Harmony Meadows Ct #1 - Photo 1 of 1

5d+ ago

House for rent in O'Fallon

DF - Harmony Meadows Ct 221 - 1

221 Harmony Meadows Ct #1, O'Fallon, MO 63368

2 beds

2 baths

$1,500

House for rent

Available Sep 19

517 Merribrook Ln - Photo 1 of 1
Rent special
3D tour

5d+ ago

House for rent in O'Fallon

Beautiful and Pet Friendly 3 Bedroom home in O'Fallon!

517 Merribrook Ln, O'Fallon, MO 63368

In-unit laundry | Storage | Assigned parking

3 beds

2 baths

$2,050

House for rent

Showing 1 - 25 of 25 results
Home > House Rentals in Defiance
Updated: March 17, 2026

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Discover houses for rent in Defiance, MO

🌇Available house rentals25 houses
💰Best rent deal221 Harmony Meadows Ct #1
🍃With outdoor space
⭐Popular amenities, ,
👚With laundry facilities
🍽With dishwasher
🚗With garage parking
❄️With air conditioning
🏠With photos